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  • Medication response: Unexpected side effects, reduced efficacy or poor tolerance to prescribed treatments.
  • Polypharmacy: Use of multiple medications with potential interaction or metabolic considerations.
  • Psychiatric medication response: Variable response to antidepressants, antipsychotics or mood stabilisers.
  • Cardiometabolic treatment: Medication use for cardiovascular conditions, diabetes or lipid regulation.
  • Pain management: Limited response or adverse reactions to analgesics or anti-inflammatory drugs.
  • Dose optimisation: Exploring whether genetic variation may influence standard dosing.
  • Pre-treatment planning: Starting long-term medication.
  • Adverse drug reactions: Previous intolerance, toxicity or treatment discontinuation.
  • Preventive medication review: Interest in safer long-term prescribing approaches.