This test requires a blood draw, so please ensure you can refer to a phlebotomist in the clients area before you order this test.
(Nordic Laboratories accepts no cost or claims related to any phlebotomy services in the event of sample rejection or failure for any reason. By ordering this, or any test requiring phlebotomy services, you accept any inherent risk and any associated costs.)
The TickPlex assay is performed on the basis of an ELISA. However, compared to other ELISA assays, this test contains a new antigen for round bodies/persister forms of Borrelia.
Elispot looks at the T cell response and IgG/IgM looks at B cells/Antibodies.
Some people don't produce antibodies and have a more active T cell response. An astounding three out of four patients with Lyme disease symptoms that are diagnosed negative for the disease following traditional criteria may respond to Borrelia persistent forms.
In an ideal world to assess an infection, a practitioner should look at both sides of the immune system response, in other words, Eli-spot for the T cells/cellular response and IgG/IgM for humoral/B cell/antibody response.
To check for an active infection with the T cells, the Elispot is recommended along with the antibodies.
TickPlex Basic is an accredited test and can be used at different stages of the disease. TickPlex Plus allows the simultaneous determination of IgM and IgG antibodies of several bacterial and viral pathogens. With its high sensitivity of approx. 95% and a specificity of 98%, TickPlex is superior to comparable IFA test methods that have been used so far.
Determination of IgM and IgG antibodies of the following bacterial and viral pathogens:
- Borrelia burgdorferi
- Borrelia afzelii
- Borrelia garinii