• Digestive symptoms: bloating, abdominal pain, diarrhoea or constipation.
• Skin symptoms: rashes, hives, acne or itching.
• Fatigue: persistent tiredness or low energy levels.
• Headaches: recurrent headaches or migraines.
• Mood symptoms: irritability, low mood or mood swings.
• Respiratory symptoms: nasal congestion, sinus issues or wheezing.
• Musculoskeletal symptoms: joint pain, stiffness or muscle aches.
• Weight concerns: unexplained weight gain or difficulty maintaining weight.
• Recurrent illness: frequent infections or prolonged recovery.
• Suspected food sensitivities: symptoms with delayed onset after eating.

Immuno IgG 115 measures IgG antibodies directed against 115 commonly consumed foods using a venous blood sample. IgG antibodies are often assessed in the context of delayed immune responses, which may develop hours or days after exposure to specific foods.

Clinically, this test may be useful when individuals present with a broad range of symptoms that appear delayed in relation to food intake and are not explained by immediate IgE-mediated allergy. The wide food coverage can help provide context for dietary patterns, particularly in individuals who eat a limited or repetitive range of foods.

Practitioners typically interpret results alongside symptom history, dietary habits, lifestyle factors and other relevant laboratory findings. When reviewed in context, the test can support informed discussions with clients about food-related immune responses and patterns that may warrant further exploration.

Practical

This test requires a blood draw, so please ensure you can refer to a phlebotomist in the clients area before you order this test.

(Nordic Laboratories accepts no cost or claims related to any phlebotomy services in the event of sample rejection or failure for any reason. By ordering this, or any test requiring phlebotomy services, you accept any inherent risk and any associated costs.)

Specimen requirements:

Serum. Blood drawn.

Specific for this test: At least 1 ml of serum

General for this lab:

- Draw blood into SST tubes until filled

- Gently invert SST tubes 2-3 times to activate clotting enhancer

- Allow blood to clot for 15 minutes undisturbed

- Centrifuge at 3000 rpm for 15 minutes

Average processing time:

14 ±7 days

Downloadable research

Eliminating Immunologically-Reactive Foods from the Diet and its Effect on Body Composition and Quality of Life in Overweight Persons

Other research

• Barnes RMR Harvey MM Blears J et al, IgG Subclass of Human Serum Antibodies Reactive with Dietary Proteins, Int Archs Allergy appl. Immun, 1986.

• Cohen GA Hartman F Hamburger RN et al, Severe Anemia and chronic Bronchitis associated with a Markedly Elevated Specific IgG to Cow’s Milk Protein, Annals of Allergy, July 1985.

• Haddad, Vetter, Friedman, Samz, Brunner, Detection and kinetics of antigen-specific IgE and IgG immune complexes in food allergy, Annal of Allergy, August 1993.

• Kemeny RD Urbanek R Amlot PL et al, Sub-class of IgG in allergic disease, I IgG subclass antibodies in immediate and non-immediate food allergy, Clinical Allergy, 1986.

• Morgan JE, Daul CB, Lehrer SB, The relationships among shrimp-specific IgG subclass antibodies and immediate adverse reactions to shrimp challenge, J Allergy Clin Immunol, September 1990.

• Niggemann, B. et al, Outcome of double-blind, placebo controlled food challenge tests in 107 children with atopic dermatitis, Clin Exp Allergy, January 1999.

• Rafei A, Peters S, Harris N, and Bellani J, Food allergy and food-specific IgG measurement, Annals of Allergy, February 1989.