• Gluten-related symptoms: Bloating, abdominal discomfort, diarrhoea or other symptoms where gluten sensitivity is being considered.
• Unclear food-related reactions: Assessment when symptoms appear linked to gluten-containing foods but patterns are inconsistent.
• Chronic digestive symptoms: Ongoing gut symptoms where gluten-related mucosal immune activity may be relevant.
• Mucosal immune assessment: Further evaluation where secretory IgA status may add useful clinical information.
• Follow-up of gluten avoidance: Reassessment in individuals reducing or avoiding gluten.
• Further dietary investigation: When symptoms persist and gluten remains part of the clinical picture.

The Gliadin Sensitivity Profile is a non-invasive test that measures salivary anti-gliadin IgA and secretory IgA. Together these markers provide information about immune reactivity to gliadin, a protein component of gluten, and mucosal immune activity.

Abnormal findings may help provide context in individuals with digestive symptoms or suspected gluten sensitivity, particularly where a mucosal immune response is being considered. Measuring secretory IgA alongside anti-gliadin antibodies can add useful clinical detail when symptoms appear food-related but are not straightforward.

Results are interpreted alongside symptom history, diet history and other relevant investigations where appropriate. The test may be useful for further dietary assessment or follow-up in individuals with ongoing gluten-related concerns.

Practical

Specimen requirements:

Serum. Blood drawn.

This test requires a blood draw, so please ensure you can refer to a phlebotomist in the clients area before you order this test.

(Nordic Laboratories accepts no cost or claims related to any phlebotomy services in the event of sample rejection or failure for any reason. By ordering this, or any test requiring phlebotomy services, you accept any inherent risk and any associated costs.)

Average processing time:

17 ±9 days (Confidence: applies to 88% of tests)

Research

Chinnery PF et al, CSF antigliadin antibodies and the Ramsay Hunt syndrome, Neurology, October 1987.