• Digestive wellness: Addressing bloating, abdominal discomfort, diarrhoea, constipation, or bowel habit changes.
• Gut regulation support: Managing IBS patterns, dysbiosis, food sensitivities, or post-infectious changes.
• Inflammatory/immune health: Considering history of IBD, coeliac disease, or immune-related gut symptoms.
• Food tolerance assessment: Evaluating responses to gluten, lactose, starches, or fibre.
• Gut-brain balance: Linking genetic influences on digestion to stress, mood, cognitive fatigue, or sleep issues.
• Barrier function support: Supportive management of influences for recurrent infections, inflammation, or intestinal permeability.
• Preventative gut health: Tailored strategies for microbiome resilience and GI maintenance.

DNA Gut is a DNA-based nutrigenetic test assessing genetic variation influencing host genetic factors involved in gastrointestinal function and microbial balance, presented as the 'five pillars' of gastrointesntial health. The panel focuses on biological systems that contribute to digestive regulation, microbial health and gut-microbiome interactions, helping practitioners explore how inherited differences may shape digestive responses,symptom patterns and gastrointestinal health.

Pathways assessed include aspects of intestinal barrier integrity, immune signalling at the gut interface, motility regulation and nutrient digestion. Genetic variation in these areas may contribute to differences in tolerance to certain foods, susceptibility to dysbiosis patterns or variation in gastrointestinal symptom presentation. Markers linked to serotonin signalling and inflammatory responses are also included to provide broader context around gut-brain communication and digestive regulation.

Results are interpreted alongside symptom history, dietary patterns, lifestyle factors and functional gut investigations where appropriate. This test pairs very well alongside fucntional gastrointestinal testing for root cause management of interventions and treatment options. Integrating genetic context with clinical assessment can support more personalised discussion around nutrition planning, microbiome support approaches and longer-term digestive health strategies.

Test type:

DNA: Gene

The test is suitable for those who are suffering from, have a family history of, or are inclined to, IBS, IBD, coeliac disease, gut dysbiosis, non-coeliac gluten sensitivity or lactose intolerance, food sensitivities, chronic bloating, diarrhoea, or constipation, autoimmune tendencies and recurrent infections, as well as mental health conditions linked to gut health including mood, cognition, and neurodegenerative conditions. It should also be considered in anyone seeking preventative, root-cause care.


Sample required:

Blood Spot

Average processing time:

18-21 days

Research
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