• Thyroid function concerns: Known or suspected thyroid issues, including hypo- or hyperthyroidism.
• Energy and metabolic concerns: Low energy, reduced stamina or unexplained weight changes.
• Mood and cognitive symptoms: Depression, low mood, memory lapses or brain fog.
• Skin, hair and nail changes: Hair loss, dry or thinning hair, brittle nails or dry skin.
• Reproductive health: Infertility, menstrual irregularities or pregnancy planning.
• Cardiovascular and fluid balance: High blood pressure or water retention.
• Environmental exposure: Known or suspected exposure to environmental pollutants affecting thyroid function.
• Nutrient status: Suspected iodine, selenium or other mineral imbalances relevant to thyroid health.

The Comprehensive Thyroid Profile (Complete Iodine Thyroid with elements) combines dried bloodspot and dried urine testing to assess thyroid hormones, thyroid antibodies and iodine-related elements. Bloodspot markers include TSH, free T4, free T3, total T4, thyroglobulin and thyroid peroxidase antibodies, while urine analysis measures iodine alongside selected elements that may influence thyroid function.

This combination allows practitioners to view thyroid hormone patterns alongside iodine status and potential elemental influences that may affect thyroid hormone synthesis and regulation. Assessing iodine excretion in urine provides insight into recent iodine intake, while concurrent blood markers offer context on thyroid hormone production and immune activity.

Practitioners typically interpret results alongside clinical history, dietary intake, supplement use, environmental exposure and other laboratory findings. Patterns are reviewed in context to support informed discussions with clients.

Practical

Specimen requirements:

Dried urine + Dried bloodspot (DBS)

Average processing time:

13 ±3 days

Research

• Als C, Minder C, Willems D, et.al. Quantification of urinary iodine: a need for revised thresholds. Eur J Clin Nutr 2003;57:1181-8.

• Haddow JE, McClain MR, Palomaki GE, Hollowell JG. Urine iodine measurements, creatinine adjustment, and thyroid deficiency in an adult United States population. J Clin Endocrinol Metab 2007;92:1019-22.

• Zava TT, Zava DT. Determination of iodine, bromine, selenium and arsenic by ICP-DRC-MS using urine dried on filter paper. Poster presented at the 83rd Annual Meeting of the American Thyroid Association, October 16-20, 2013, San Juan, Puerto Rico.