• Digestive symptoms: bloating, belching, abdominal pain or changes in bowel habits.
• Bowel pattern changes: diarrhoea, constipation or alternating stool patterns.
• Food-related reactions: suspected delayed responses following food intake.
• Skin concerns: rashes, hives or acne with possible dietary associations.
• Respiratory symptoms: congestion, wheezing or recurrent upper airway irritation.
• Neurological symptoms: headaches, dizziness or poor concentration.
• Energy changes: fatigue, lethargy or reduced stamina.
• Mood and behaviour changes: irritability, anxiety or low mood.
• Weight changes: unexplained weight gain, difficulty losing weight or being underweight.
• Joint and muscle discomfort: stiffness, aches or reduced mobility.
• Gluten-related concerns: digestive or systemic symptoms linked to gluten-containing foods.
• Recurrent symptoms: patterns that persist despite dietary or lifestyle adjustments.

The Immuno 1 IgG 115 + Gliadin test measures IgG antibodies to a broad panel of 115 commonly consumed foods together with IgG and IgA antibodies to gliadin. The test is performed using ELISA technology on a serum blood sample and provides information on immune antibody responses to foods and to the gluten-derived protein gliadin.

Clinically, this test may be useful when symptoms raise questions about delayed food-related immune responses or possible gluten-related reactivity. Reviewing antibody patterns across a wide range of foods and gliadin may help practitioners observe associations between dietary intake and digestive, skin, respiratory, neurological or energy-related symptoms.

Practitioners typically interpret results alongside dietary history, symptom patterns, lifestyle factors, medication use and other laboratory findings. When considered together, this information can support structured discussions with clients about dietary patterns, food exposure and potential next steps for dietary exploration.

Practical

Specimen requirements:

Serum. Blood drawn.

This test requires a blood draw, so please ensure you can refer to a phlebotomist in the clients area before you order this test.

(Nordic Laboratories accepts no cost or claims related to any phlebotomy services in the event of sample rejection or failure for any reason. By ordering this, or any test requiring phlebotomy services, you accept any inherent risk and any associated costs.)

Average processing time:

17 ±9 days

Research related to IgG 115

• Barnes RMR Harvey MM Blears J et al, IgG Subclass of Human Serum Antibodies Reactive with Dietary Proteins, Int Archs Allergy appl. Immun, 1986.

• Cohen GA Hartman F Hamburger RN et al, Severe Anemia and chronic Bronchitis associated with a Markedly Elevated Specific IgG to Cow’s Milk Protein, Annals of Allergy, July 1985.

• Haddad, Vetter, Friedman, Samz, Brunner, Detection and kinetics of antigen-specific IgE and IgG immune complexes in food allergy, Annal of Allergy, August 1993.

• Kemeny RD Urbanek R Amlot PL et al, Sub-class of IgG in allergic disease, I IgG subclass antibodies in immediate and non-immediate food allergy, Clinical Allergy, 1986.

• Morgan JE, Daul CB, Lehrer SB, The relationships among shrimp-specific IgG subclass antibodies and immediate adverse reactions to shrimp challenge, J Allergy Clin Immunol, September 1990.

• Niggemann, B. et al, Outcome of double-blind, placebo controlled food challenge tests in 107 children with atopic dermatitis, Clin Exp Allergy, January 1999.

• Rafei A, Peters S, Harris N, and Bellani J, Food allergy and food-specific IgG measurement, Annals of Allergy,

February 1989.

Research related to Gliadin

• Chinnery PF et al, CSF antigliadin antibodies and the Ramsay Hunt syndrome, Neurology, October 1987.