• Food-related symptoms: bloating, abdominal pain, diarrhoea or constipation.
• Skin symptoms: rashes, hives, acne or itching.
• Fatigue: persistent tiredness or low energy levels.
• Headaches: recurrent headaches or migraines.
• Respiratory symptoms: nasal congestion, sneezing, wheezing or asthma-like symptoms.
• Musculoskeletal symptoms: joint pain, stiffness or muscle aches.
• Neurological symptoms: poor concentration, memory difficulties or dizziness.
• Weight concerns: unexplained weight gain or difficulty gaining weight.
• Recurrent infections: frequent illness or slow recovery.
• Dietary patterns: symptoms that appear delayed after eating certain foods.

Immuno 1 IgG 115 + Candida combines measurement of IgG antibodies to 115 commonly consumed foods with assessment of antibodies associated with Candida exposure, using a venous blood sample. IgG antibodies are commonly evaluated in the context of delayed immune responses, while Candida-related antibodies provide information about immune recognition of yeast antigens.

Clinically, this combined panel may be useful when individuals present with a wide range of symptoms that appear delayed after food intake or are not explained by immediate IgE-mediated allergy. Food-specific IgG antibodies are often explored in relation to digestive, skin, neurological or systemic symptoms that develop hours or days after exposure.

Practitioners typically interpret results alongside symptom history, dietary patterns, medication use and other relevant laboratory findings. When reviewed in context, the test can support informed discussions with clients about dietary exposures, immune responses and patterns that may warrant further exploration.

Practical

Specimen requirements:

Serum. Blood drawn.

This test requires a blood draw, so please ensure you can refer to a phlebotomist in the clients area before you order this test.

(Nordic Laboratories accepts no cost or claims related to any phlebotomy services in the event of sample rejection or failure for any reason. By ordering this, or any test requiring phlebotomy services, you accept any inherent risk and any associated costs.)

Average processing time:

17 ±9 days

Research related to IgG 115

• Barnes RMR Harvey MM Blears J et al, IgG Subclass of Human Serum Antibodies Reactive with Dietary Proteins, Int Archs Allergy appl. Immun, 1986.

• Cohen GA Hartman F Hamburger RN et al, Severe Anemia and chronic Bronchitis associated with a Markedly Elevated Specific IgG to Cow’s Milk Protein, Annals of Allergy, July 1985.

• Haddad, Vetter, Friedman, Samz, Brunner, Detection and kinetics of antigen-specific IgE and IgG immune complexes in food allergy, Annal of Allergy, August 1993.

• Kemeny RD Urbanek R Amlot PL et al, Sub-class of IgG in allergic disease, I IgG subclass antibodies in immediate and non-immediate food allergy, Clinical Allergy, 1986.

• Morgan JE, Daul CB, Lehrer SB, The relationships among shrimp-specific IgG subclass antibodies and immediate adverse reactions to shrimp challenge, J Allergy Clin Immunol, September 1990.

• Niggemann, B. et al, Outcome of double-blind, placebo controlled food challenge tests in 107 children with atopic dermatitis, Clin Exp Allergy, January 1999.

• Rafei A, Peters S, Harris N, and Bellani J, Food allergy and food-specific IgG measurement, Annals of Allergy,

February 1989.

Research related to Candida

• Abu-Elteen KH. The influence of dietary carbohydrates on in vitro adherence of four Candida species to human buccal epithelial cells. Microb Ecol Health Dis 2005; 17: 156-62.

• Jarvis WR. Epidemiology of Nosocomial Fungal Infections, with Emphasis on Candida Species. Clinical Infectious Diseases. 1995;20(6):1526-1530.

• Kennedy, M. J. and Volz, P.A., Effect of various antibiotics on gastrointestinal colonization and dissemination by Candida albicans, Sabouraudia, 23, 265–274, 1985.

• Lehmann PF, Reiss E. Comparison by Elisa of serum anti-Candida albicans mannan IgG levels of a normal population and in diseased patients. Mycopathologia. 1980;70(2):89-93.

• Montagna MT, Caggiano G, Borghi E, Morace G. The Role of the Laboratory in the Diagnosis of Invasive Candidiasis. Drugs. 2009;69(Supplement 1):59-63.

• Pires MFC, Corra B, Gambale W, Paula CR. Experimental model of Candida albicans (serotypes A and B) adherence in vitro. Braz J Microbiol 2001; 32: 163-9.

• Pizzo G, Giuliana G, Milici ME, Giangreco R. Effect of dietary carbohydrates on the epithelial adhesion of Candida albicans, Candida tropicalis, and Candida krusei. New Microbiol 2000; 23: 63-71.

• Seelig MS. The role of antibiotics in the pathogenesis of Candida infections. The American Journal of Medicine. 1966;40(6):887-917.

• Seligmann, E., Virulence enhancement of Candida albicans by antibiotics and cortisone. Proc. Soc. Exp. Biol. Med., 1953. 83: p. 778–781. 68.

• Vojdani A, Rahimian P, Kalhor H, Mordechai E. Immunological cross reactivity between Candida albicans and human tissue. J Clin Lab Immunol. 1996;48(1):1-15.